Urea crystals obtained from AdBlue
Ball and stick model of urea.
| IUPAC name
| Systematic IUPAC name
| Other names
|Molar mass||60.06 g/mol|
|Melting point||133–135 °C (271–275 °F; 406–408 K)|
| 107.9 g/100 ml (20 °C)
167 g/100 ml (40 °C)
251 g/100 ml (60 °C)
400 g/100 ml (80 °C)
|Solubility|| Soluble in glacial acetic acid
Insoluble in benzene, toluene, xylene
|Solubility in acetonitrile||0.4 g/100 ml|
|Solubility in ethanol||5 g/100 ml|
|Solubility in glycerol||50 g/100 ml|
|Solubility in methanol||16.6 g/100 ml|
Std enthalpy offormation (ΔfH
|Safety data sheet||Sigma-Aldrich|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|8500 mg/kg (oral, rat)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Urea or carbamide, is an organic compound commonly used as a fertilizer. It has the chemical formula (NH2)2CO. Urea was the first organic chemical produced from inorganic chemicals, a breakthrough in chemistry, which proved organic substances can be produced from inorganic substances, disproving the notion of vitalism.
Thermal decomposition of urea produces ammonium isocyanate, who in turn yields isocyanuric acid.
- NH2CONH2 → NH4NCO → HNCO + NH3
Urea is a weak organic base. It forms salts with strong acids. Despite its two amino groups, it acts as a monoprotic base, only accepting one H+ cation. With diprotic acids such as sulfuric, urea forms two types of salts: monocarbamide dihydrosulfate (carbamonium bisulfate, analogous to inorganic bisulfates) and dicarbamide dihydrosulfate (carbamonium sulfate, analogous to inorganic sulfates).
A frequent contaminant of urea is biuret. A high concentration of biuret mitigates against using urea as a crop fertilizer, but makes it more valuable as an animal feed additive.
Urea is a white crystalline substance. Its melting point is between 133-135 °C. Urea is soluble in water (107.9 g/100 ml at 20 °C) and when dissolved, it is neutral on the pH scale. Urea is soluble in glycerol (500 g/L) and slightly less soluble in ethanol. Urea is soluble in dimethyl sulfoxide (40 g/100 ml at 20-30 °C, 110 g/100 ml at 90-100 °C). 
Urea is available as a fertilizer, either pure or mixed with other substances. It can be very cheaply purchased online, often at less than $5/kg. Most of the OTC urea is coated with a special coating which slows its release in the soil, to prevent fertilizer burn. Recrystallization is required to remove this coating.
ScienceCompany sells 500g of lab grade urea at 16.95 $.
AdBlue, used for reduction of nitrous oxide gases from car exhausts, is a quite strong solution of urea in water with little other additives.
- AgOCN + NH4Cl → (NH2)2CO + AgCl
Industrially it is produced by the thermal decomposition of ammonium carbamate.
- COCl2 + 4 NH3 → (NH2)2CO + 2 NH4Cl
|Urea reacts with:||catalyst||solvent||product||reaction notes|
|Nitric acid||water||urea nitrate||exothermic|
|Potassium nitrate ||hydrochloric acid||water||urea nitrate||replacement|
|Hydrogen peroxide||water||urea peroxide||exothermic|
|Citric acid ||water||urea citrate|
|Sodium carbonate||water||sodium cyanate||produces ammonia gas|
|Malonic acid and sodium ethoxide||anhydrous ethanol||barbituric acid||condensation|
- Urea nitrate synthesis
- Sodium azide synthesis
- Hydrazine sulfate(Hoffman Rearrangement)
- Calcium cyanamide synthesis
- Thermal decomposition of molten urea to biuret and ammonia.
- Make sodium cyanate and sodium cyanide
Urea is non-toxic, though is may cause irritations to sensitive tissues. It may corrode metallic surfaces, even the more resistant forms of stainless steel.
Urea doesn't require any special storage, and can be safely stored in glass, metal, plastic or ceramic containers. Make sure to keep it in a dry place, as urea will absorb water from air and harden itself after a while, if kept in a moist place.
As urea is a good fertilizer, it can be safely dumped in the soil, although it's recommended to avoid dumping it in water reservoirs to prevent the growth on unwanted algae. It can also be used to as a nitrogen source for aerobic bacteria in the conversion of sawdust to compost.
- http://www.gaylordchemical.com/uploads/images/pdfs/literature/102B_english.pdf Gaylord Chemical Company
- Making Urea Nitrate without Nitric Acid